The Cell Recognition Factor Theory is Fast Heading Towards Vindication

"The authors concluded that human colon-cancer stem cells are defined not by their intrinsic gene-expression patterns, but by their location."

"if these same cells are removed from adult tissues, they quickly reactivate multipotency, or the ability to differentiate into discrete cell types, including cancerous ones, reinforcing the tissue environment’s crucial role in tumor development."

"...suggesting that the tissue environment plays a part in defining stem cells."

https://www.nature.com/articles/d41586-021-01029-4?utm_source=Nature+Briefing&utm_campaign=908962649e-briefing-dy-20210421&utm_medium=email&utm_term=0_c9dfd39373-908962649e-45862826

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