Beta-catenin Overexpressed in Skin Cancer

[I've taken the plunge and bought myself an online subscription to Nature and 50+ other publications they produce. This will mean more posts on this blog]

This is a quick read. The researchers found that beta-catenin was over-expressed in skin cancer while in normal stem cells, it is only expressed periodically.

This falls inline with the CRF theory. Beta-catenin is an essential player in how the cell reprograms itself by implementing epigenetic changes. Clearly, a cancer cell, having difficulty establishing contact with the proper CRF's, might continue to express beta-catenin because the embryonic CRF's are nowhere to be found.

Baker, M. Skin cancer needs beta-catenin. Nat Rep Stem Cells (2008). https://doi.org/10.1038

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